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Results and Repeatability of Retinal Thickness Measurements From Certification Submissions
Ronald P. Danis, MD;
Marian R. Fisher, PhD;
Ericka Lambert, BA;
Anne Goulding, BA;
Deborah Wu, MD;
Li-Yin Lee, MS
Arch Ophthalmol. 2008;126(1):45-50.
Objectives To present the results for subgroups defined by center point (CP) measurement and to assess the repeatability of the Fast Retinal Thickness Map analysis results from the Stratus OCT3 machine.
Methods Two hundred eighty-one replicate OCT3 scans from 134 operators' certification submissions to a reading center were analyzed, including scans from eyes that were reported to be normal and eyes with exudative age-related macular degeneration and with macular edema due to diabetic retinopathy or retinal vascular occlusion.
Results The mean (SD) of the CP was 284 (150) µm and the center subfield (CC) was 301 (130) µm. The CP coefficient of repeatability (CR) was 49 µm and the CC CR was 27 µm. The CR increased by increasing retinal thickness for the CP and the CC within arbitrarily defined subgroups. For the 87 eyes with a session 1 CP of 175 µm or less, the CP CR was 17 µm and the CC CR was 10 µm.
Conclusions Among experienced operators, given the same operator, machine, and eye at the same sitting, OCT3 retinal thickness maps appear to have a CR that is likely to be less than the clinically important difference.
Author Affiliations: Departments of Ophthalmology and Visual Sciences (Drs Danis and Wu and Mss Lambert, Goulding, and Lee) and Biostatistics and Medical Informatics (Dr Fisher), University of Wisconsin–Madison School of Medicine and Public Health.
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