You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 124 No. 3, March 2006 TABLE OF CONTENTS
  Archives
  •  Online Features
  Laboratory Sciences
 This Article
 •Full text
 •PDF
 • Reply to article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal
 Topic Collections
 •Corneal Disorders
 •Laser Surgery
 •Randomized Controlled Trial
 •Alert me on articles by topic
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit Add to Technorati Add to Twitter What's this?

Demonstration of Aqueous Streaming Through a Laser Iridotomy Window Against the Corneal Endothelium

Yasuaki Yamamoto, MD; Toshihiko Uno, MD, PhD; Katsumi Shisida, MD; Longquan Xue, MD; Atsushi Shiraishi, MD, PhD; Xiaodong Zheng, MD, PhD; Yuichi Ohashi, MD, PhD

Arch Ophthalmol. 2006;124:387-393.

Objective  To determine the pathogenesis of the bullous keratopathy that is frequently observed in patients after argon laser iridotomy (ALI) by comparing the changes in aqueous flow after ALI with those that follow peripheral iridectomy in rabbit eyes.

Methods  Silicone particles were injected into the anterior chamber of rabbit eyes as tracers to monitor aqueous flow. Particle tracking velocimetry with image analysis was used to determine the direction and speed of aqueous flow in 5 pigmented rabbits that underwent ALI and 5 that underwent peripheral iridectomy.

Results  In the ALI group, silicone particles were found to stream through the iridotomy window against the corneal endothelium immediately after the pupil was constricted by a light stimulus. The mean ± SD speed of the particles was 2.97 ± 1.51 mm/s. In contrast, the mean ± SD flow rate through the iridectomy window in the peripheral iridectomy group was significantly slower at 0.36 ± 0.30 mm/s (P = .01).

Conclusion  Constriction of the pupil elicited marked aqueous streaming through the ALI window against the corneal endothelium.

Clinical Relevance  The mechanical stress to the corneal endothelium by the abnormal aqueous stream may be partially responsible for the corneal decompensation that follows ALI.


Author Affiliations: Departments of Ophthalmology, Ehime University, Shitsukawa, Toon-city, Ehime (Drs Yamamoto, Uno, Shisida, Xue, Shiraishi, Zheng, and Ohashi), and Takanoko Hospital, Matsuyama City (Drs Yamamoto and Shiraishi), Japan.



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Posterior chamber volume does not change significantly during dilation
Dorairaj et al.
Br J Ophthalmol 2009;93:1514-1517.
ABSTRACT | FULL TEXT  

Late irreversible corneal oedema after laser iridotomy
Shimazaki et al.
Br J Ophthalmol 2009;93:125-126.
FULL TEXT  

Authors' response
Kinoshita et al.
Br J Ophthalmol 2008;92:1300-1301.
FULL TEXT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 2006 American Medical Association. All Rights Reserved.