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Intravitreal Triamcinolone

Andrew C. Westfall, MD; Alexander Osborn, PhD; Derek Kuhl, PhD, MD; Matthew S. Benz, MD; William F. Mieler, MD; Eric R. Holz, MD

Arch Ophthalmol. 2005;123:1075-1077.

Objective  To report the incidence of acute postinjection endophthalmitis following intravitreal injection of triamcinolone acetonide (IVTA) as an office procedure.

Methods  Retrospective, noncomparative, consecutive, interventional case series of all patients who had received IVTA at 2 clinical centers between January 1, 2000, and January 30, 2004.

Results  A total of 1006 eyes received IVTA. None of the eyes developed acute, culture-positive, postoperative endophthalmitis in the 6 weeks following the procedure. One patient developed acute, culture-negative, postoperative endophthalmitis 4 days after receiving IVTA, resulting in an incidence of 0.10%. In this case, the presenting symptoms were decreased vision and acute conjunctival erythema. The case was notable for the absence of pain or hypopyon.

Conclusion  Although acute postoperative endophthalmitis may follow IVTA, our experience suggests that this is a relatively uncommon event.

Author Affiliations: Department of Ophthalmology, Baylor College of Medicine, Houston, Tex (Drs Westfall, Osborn, Benz, Mieler, and Holz); and Austin Retina Associates, College Station, Tex (Dr Kuhl). Dr Mieler is now with the Department of Ophthalmology, University of Chicago, Chicago, Ill.

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