This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on ISI (1)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Ocular/ Adnexal Tumors  • Retinal/ Chorioretinal Disorders  • Alert me on articles by topic

David H. Abramson, MD; Mark R. Melson, MD; Camille Servodidio, RN, MPH, CRNO

Arch Ophthalmol. 2004;122:1324-1330.

Objective  To describe the visual field defects in retinoblastoma survivors and relate those defects to characteristics such as tumor size, tumor location, and treatment modality.

Methods  Thirty-one patients treated for retinoblastoma were included in this study. Humphrey visual fields were determined in 33 eyes.

Results  Twenty-seven patients (29 eyes, 68 tumors) had sufficient diagnosis and treatment data available for further analysis. Twenty-six of the 27 patients had both absolute and relative visual field defects. Four types of visual field defects were observed and correlated with location of the tumor and therapy to the individual tumors: (1) no residual defect, (2) absolute scotoma, (3) arcuate and sector scotoma, and (4) "pseudo"–visual field defects caused by relative enophthalmos resulting from radiation.

Conclusions  Patients with retinoblastoma demonstrate a variety of long-term visual field defects after treatment for their intraocular disease. Characteristics that determine the size and type of defects are tumor size, tumor location, and treatment method.

From the Ophthalmology Oncology Service, Departments of Surgery, Radiation Oncology, and Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY (Dr Abramson); Massachusetts Eye and Ear Infirmary, Boston (Dr Melson); and Department of Radiation Oncology, Hartford Hospital, Hartford, Conn (Ms Servodidio). The authors have no relevant financial interest in this article.