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  Vol. 122 No. 7, July 2004 TABLE OF CONTENTS
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Corneal Changes After Small-Incision Cataract Surgery in Patients With Diabetes Mellitus

Soichi Morikubo, MD; Yoshihiro Takamura, MD, PhD; Eri Kubo, MD, PhD; Shosai Tsuzuki, MD, PhD; Yoshio Akagi, MD, PhD

Arch Ophthalmol. 2004;122:966-969.

Objective  To evaluate functional impairment in the corneal endothelium of eyes in patients with diabetes mellitus, after small-incision cataract surgery.

Methods  Evaluation was performed in 93 eyes in patients with type 2 diabetes mellitus (diabetic group) and 93 eyes in patients without diabetic mellitus (nondiabetic group) who underwent cataract surgery. Using a topography system, the corneal thickness in the central area was measured before surgery and 1 day, 1 week, and 1 month after surgery. Corneal endothelial cells were counted using a noncontact specular microscope.

Results  No significant differences in any preoperative measures were observed between the diabetic and nondiabetic groups. The increase in corneal thickness 1 month after surgery was significantly higher in the diabetic group than in the nondiabetic group (P = .03). The corneal endothelial cell losses 1 day and 1 week after surgery were significantly higher in the diabetic group than in the nondiabetic group (after 1 day, P = .03; and after 1 week, P = .04).

Conclusion  Compared with nondiabetic eyes, eyes of patients with diabetes mellitus showed more damage in corneal endothelial cells due to cataract surgery and a delay in the postoperative recovery of corneal edema.


From the Division of Ophthalmology, School of Medicine, Fukui University, Fukui, Japan. The authors have no relevant financial interest in this article.



THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Proteinase and Growth Factor Alterations Revealed by Gene Microarray Analysis of Human Diabetic Corneas
Saghizadeh et al.
IOVS 2005;46:3604-3615.
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Risk Factors for Corneal Endothelial Injury During Small-Incision Cataract Surgery in Patients With Diabetes Mellitis
Tsai et al.
Arch Ophthalmol 2005;123:1020-1021.
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