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Allen B. Thach, MD; Jack O. Sipperley, MD; Pravin U. Dugel, MD; Scott R. Sneed, MD; Donald W. Park, MD; Jennifer Cornelius, BS

Arch Ophthalmol. 2003;121:817-820.

Objective  To describe the outcome of patients with occult choroidal neovascularization in age-related macular degeneration treated with transpupillary thermotherapy.

Design  Prospective, nonrandomized, nonmasked case series.

Methods  All patients with age-related macular degeneration with a predominantly occult choroidal neovascular membrane and an initial visual acuity of 20/400 or better were offered treatment using transpupillary thermotherapy. The treatment consisted of using a diode laser, a spot size of about 3000 to 6000 µm delivered over 60 seconds, and a power of 600 to 1000 mW.

Main Outcome Measures:  A stable, improved, or worsened visual acuity and the need for additional treatment.

Results  Sixty-nine patients were treated. All patients have been followed up for at least 6 months. At the 6-, 9-, and 12-month follow-up visits, 71% of patients have stable or improved visual acuity and 29% have lost 2 or more lines of visual acuity on the Snellen letter chart.

Conclusion  Large–spot size transpupillary thermotherapy is effective in stabilizing the visual acuity in those patients who have occult choroidal neovascularization due to age-related macular degeneration.

From the Retinal Consultants of Arizona, Phoenix.

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