 |
|
Corneal Thickness and Intraocular Pressure in the Barbados Eye Studies
Barbara Nemesure, PhD;
Suh-Yuh Wu, MA;
Anselm Hennis, MRCP(UK), PhD;
M. Cristina Leske, MD, MPH;
for the Barbados Eye Study Group
Arch Ophthalmol. 2003;121:240-244.
Objectives To describe the distribution of central corneal thickness (CCT) and evaluate its relationship to intraocular pressure (IOP) in the predominantly black population of the Barbados Eye Studies (BES).
Methods Participants received a standardized examination, including pachymetry, applanation tonometry, and a comprehensive ophthalmologic evaluation. Analyses were based on data from all eyes, and generalized estimating equation methods were applied to account for the correlation between eyes.
Results Among the 1142 consecutive participants with pachymetry measurements, the mean age was 64.3 years, and 58% were women. Black participants tended to have thinner corneas (mean thickness, 529.8 µm) than mixed (black and white) (537.8 µm) and white participants (545.2 µm), respectively. Among black participants, increasing values of CCT were significantly related to younger age (P<.001), diabetes history (P = .03), and refractive error (P = .03); a marginally significant relationship (with thinner corneas) was found with a clinical diagnosis of glaucoma (P = .07). Intraocular pressure was not associated with CCT in this population.
Conclusions Although other studies have reported a positive correlation between CCT and IOP, such a relationship was not substantiated in the black BES population. Black participants tended to have thinner corneas than white participants, whereas younger individuals, as well as those with a history of diabetes and more positive refractive errors, had thicker corneas.
From the University Medical Center, Stony Brook, NY (Drs Nemesure, Wu, Hennis, and Leske); the Ministry of Health and University of the West Indies, Barbados, West Indies (Dr Hennis); The Johns Hopkins University, Baltimore, Md; for the Barbados Eye Study Group.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
|
Nine-year changes in intraocular pressure: the barbados eye studies.
Wu et al.
Arch Ophthalmol 2006;124:1631-1636.
ABSTRACT
| FULL TEXT
Longitudinal changes in central corneal thickness and their relation to glaucoma status: an 8 year follow up study
Weizer et al.
Br. J. Ophthalmol. 2006;90:732-736.
ABSTRACT
| FULL TEXT
Detection of psychophysical and structural injury in eyes with glaucomatous optic neuropathy and normal standard automated perimetry.
Bagga et al.
Arch Ophthalmol 2006;124:169-176.
ABSTRACT
| FULL TEXT
Prevalence of Open-Angle Glaucoma in a Rural South Indian Population
Vijaya et al.
IOVS 2005;46:4461-4467.
ABSTRACT
| FULL TEXT
Central Corneal Thickness Is Highly Heritable: The Twin Eye Studies
Toh et al.
IOVS 2005;46:3718-3722.
ABSTRACT
| FULL TEXT
The influence of central corneal thickness and age on intraocular pressure measured by pneumotonometry, non-contact tonometry, the Tono-Pen XL, and Goldmann applanation tonometry
Tonnu et al.
Br. J. Ophthalmol. 2005;89:851-854.
ABSTRACT
| FULL TEXT
Corneal Thickness Determination and Correlates in Singaporean Schoolchildren
Tong et al.
IOVS 2004;45:4004-4009.
ABSTRACT
| FULL TEXT
Clinical Significance of Central Corneal Thickness in the Management of Glaucoma
Shih et al.
Arch Ophthalmol 2004;122:1270-1275.
ABSTRACT
| FULL TEXT
Association of Corneal Thickness and Intraocular Pressure
Aref
Arch Ophthalmol 2004;122:425-425.
FULL TEXT
Association of Corneal Thickness and Intraocular Pressure--Reply
Nemesure et al.
Arch Ophthalmol 2004;122:425-426.
FULL TEXT
Central Corneal Thickness as a Risk Factor for Advanced Glaucoma Damage
Herndon et al.
Arch Ophthalmol 2004;122:17-21.
ABSTRACT
| FULL TEXT
|
