You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 121 No. 12, December 2003 TABLE OF CONTENTS
  Archives
  •  Online Features
  Clinical Sciences
 This Article
 •Full text
 •PDF
 • Reply to article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Citing articles on Web of Science (29)
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal
 Topic Collections
 •Glaucoma
 •Ocular Imaging
 •Radiologic Imaging
 •Prognosis/ Outcomes
 •Alert me on articles by topic
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit Add to Technorati Add to Twitter What's this?

Ocular Hemodynamics and Glaucoma Prognosis

A Color Doppler Imaging Study

Fernando Galassi, MD; Andrea Sodi, MD; Francesca Ucci, MD; Giulia Renieri, MD; Benedetta Pieri, MD; Michela Baccini, PhD

Arch Ophthalmol. 2003;121:1711-1715.

Objective  To evaluate the effect of optic nerve circulation, using color Doppler imaging (CDI), on the progression of visual field damage in primary open-angle glaucoma.

Methods  The relationship between the results of retrobulbar CDI, performed shortly after the diagnosis of primary open-angle glaucoma, and the progression of visual field loss for 7 years was evaluated in 44 glaucoma patients. Color Doppler imaging variables in patients with a stable and deteriorating clinical course were compared, and the pattern of increasing risk for different CDI values was analyzed using an additive logistic model. Based on this nonparametric analysis, we arrived at a discriminant CDI value identifying glaucoma patients with a poor prognosis. On the basis of the discriminant value, patients were divided into 2 groups, and the odds ratio of visual field loss for each group was then estimated.

Results  Patients with a stable visual field had a higher diastolic velocity and a lower resistivity index in the ophthalmic artery (P<.001 for both) compared with those with a deteriorating visual field during the study. The odds of visual field deterioration in patients with an ophthalmic artery resistivity index of 0.78 or higher was about 6 times that of patients with an ophthalmic artery resistivity index lower than 0.78.

Conclusion  Color Doppler imaging variables of the ophthalmic artery correlate with the risk of visual field deterioration in patients with primary open-angle glaucoma.


From the Departments of Oto-Neuro-Ophthalmological Surgery (Drs Galassi, Sodi, Ucci, Renieri, and Pieri) and Statistics (Dr Baccini), University of Florence, Italy. The authors have no commercial or proprietary interest in the products used in this study.



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Twenty-four Hour Ocular Perfusion Pressure Fluctuation and Risk of Normal-Tension Glaucoma Progression
Sung et al.
IOVS 2009;50:5266-5274.
ABSTRACT | FULL TEXT  

Peripheral Artery Disease and Glaucoma: The Singapore Malay Eye Study
Jeganathan et al.
Arch Ophthalmol 2009;127:888-893.
ABSTRACT | FULL TEXT  

Estimation of Ocular Rigidity Based on Measurement of Pulse Amplitude Using Pneumotonometry and Fundus Pulse Using Laser Interferometry in Glaucoma
Hommer et al.
IOVS 2008;49:4046-4050.
ABSTRACT | FULL TEXT  

Ocular blood flow in glaucoma: the need for further clinical evidence and patient outcomes research
Stewart et al.
Br J Ophthalmol 2007;91:1263-1264.
FULL TEXT  

Evaluation of ocular surface temperature and retrobulbar haemodynamics by infrared thermography and colour Doppler imaging in patients with glaucoma
Galassi et al.
Br J Ophthalmol 2007;91:878-881.
ABSTRACT | FULL TEXT  

Glaucoma progression is associated with decreased blood flow velocities in the short posterior ciliary artery
Zeitz et al.
Br J Ophthalmol 2006;90:1245-1248.
ABSTRACT | FULL TEXT  

Evaluation of Differences Between Observers and Automatic-Manual Measurements in Calculation of Doppler Parameters
Unal et al.
J Ultrasound Med 2004;23:1041-1048.
ABSTRACT | FULL TEXT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 2003 American Medical Association. All Rights Reserved.