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A 50th Anniversary Tribute to the Contributions of Helenor Campbell Wilder Foerster

Gary N. Holland, MD; Kevan G. Lewis, MS; G. Richard O'Connor, MD

Arch Ophthalmol. 2002;120:1081-1084.

In 1952, Helenor Campbell Wilder (later Helenor Campbell Wilder Foerster) confirmed the growing suspicion that Toxoplasma gondii was a cause of uveitis in otherwise healthy adults by identifying the presence of parasites in eyes enucleated because of severe intraocular inflammation. Ocular toxoplasmosis was previously known to occur only in newborns with congenital T gondii infection. Her report ushered in a new era in the field of uveitis in which toxoplasmosis, rather than tuberculosis, was confirmed to be the most common cause of retinochoroiditis. Fifty years later, issues raised in her landmark publication are still being investigated.

From the Ocular Inflammatory Disease Center, Jules Stein Eye Institute, and Department of Ophthalmology, University of California, Los Angeles, UCLA School of Medicine, Los Angeles, Calif (Dr Holland and Mr Lewis); and the Francis I. Proctor Foundation for Research in Ophthalmology and Department of Ophthalmology, University of California, San Francisco, School of Medicine, San Francisco (Dr O'Connor).

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