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The SEE Project

Arch Ophthalmol. 2002;120:774-780.

Objective  To determine the association between performance on selected tasks of everyday life and impairment in visual acuity and contrast sensitivity.

Methods  Visual acuity and contrast sensitivity were obtained on a population-based sample of 2520 older African American and white subjects. Performance was assessed on mobility, daily activities with a strong visual component, and visually intensive tasks. Disability was defined as performance less than 1 SD below the mean. Receiver operating characteristic curve analyses were used to evaluate the sensitivity and specificity of thresholds in acuity and contrast loss for determining disability.

Results  Both visual acuity and contrast sensitivity loss were associated with decrements in function. The relationship of function to the vision measures was mostly linear, therefore, receiver operating characteristic curves were not helpful in identifying cutoff points for predicting disabilities. For mobility tasks, most persons were not disabled until they had significant acuity loss (logMAR visual acuity >1.0 or <20/200) or contrast sensitivity loss (0.9 log units contrast sensitivity). For heavily visually intensive tasks, like reading, visual acuity worse than 0.2 logMAR (20/30) or contrast sensitivity worse than 1.4 log units was disabling.

Conclusions  Both contrast sensitivity and visual acuity loss contribute independently to deficits in performance on everyday tasks. Defining disability as deficits in performance relative to a population, it is possible to identify visual acuity and contrast loss where most are disabled. However, the cutoff points depend on the task, suggesting that defining disability using a single threshold for visual acuity or contrast sensitivity loss is arbitrary.

Sheila K. West, PhD; Gary S. Rubin, PhD; Aimee T. Broman, MS; Beatriz Muñoz, MSc; Karen Bandeen-Roche, PhD; Kathleen Turano, PhD; for the SEE Project Team
From the Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Md (Dr West and Mss Broman and Muñoz); Institute of Ophthalmology, University College, London, England (Dr Rubin); Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore (Dr Bandeen-Roche); and Lions Low Vision Center, Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore (Dr Turano).

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