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Causes of Incident Visual Impairment
The Blue Mountains Eye Study
Arch Ophthalmol. 2002;120:613-619.
Objective To describe the causes of 5-year incident visual impairment and doubling
of the visual angle in a population-based cohort.
Methods Of the 3654 participants aged older than 50 years who participated in
the Blue Mountains Eye Study (BMES I, 1992-1994), 543 died and 2335 were reexamined
between 1997 and 1999 (BMES II). Visual acuity was measured using a logMAR
chart before and after refraction. Pupils were dilated, and a detailed eye
examination was performed. For participants with incident visual impairment
or doubling of the visual angle, an ophthalmologist attributed and proportioned
causes. Primary causes were defined as those responsible for 50% or more of
the impairment.
Results After refractive correction, the proportion of incident bilateral impairment
worse than 20/40, worse than 20/70, and worse than 20/200 that were caused
primarily by cataract decreased from 51.4% (n = 19) to 40.0% (n = 6) to 0%;
while the proportion of cases caused primarily by age-related maculopathy
increased from 24.3% (n = 9) to 33.3% (n = 5) to 100.0% (n = 2). Similarly,
the corresponding proportions of incident unilateral impairment caused primarily
by cataract decreased from 53.7% (n = 72) to 36.9% (n = 31) to 13.6% (n =
6); meanwhile, the proportion of cases caused primarily by age-related maculopathy
increased from 19.4% (n = 26) to 32.1% (n = 27) to 54.5% (n = 24). The proportions
of persons with incident bilateral impairment worse than 20/40, worse than
20/70, and worse than 20/200 that could be improved with refraction were 79.4%
(n = 143), 73.6% (n = 42), and 0%, respectively. The corresponding proportions
of incident unilateral impairment improved by refraction were 66.7% (n = 269),
59.0% (n = 121), and 21.4% (n = 12).
Conclusion This study has documented the 5-year incidence and causes of visual
impairment in an older Australian population.
Suriya Foran, MBBS, MPH;
Jie Jin Wang, MMed, PhD;
Paul Mitchell, MD, PhD
From the Department of Ophthalmology, Centre for Vision Research, Westmead
Hospital, Sydney, Australia, and the Save Sight and Westmead Millennium Institutes,
the University of Sydney, Sydney.
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