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Vincent J. Hoye III, MD; Audina M. Berrocal, MD; Thomas R. Hedges III, MD; Maria Luz Amaro-Quireza, OD

Arch Ophthalmol. 2001;119:1287-1290.

Objective  To evaluate macular changes in eyes with papilledema from increased intracranial pressure using optical coherence tomography (OCT).

Methods  Fifty-five patients with papilledema seen during 1998 and 1999 were studied with OCT of the optic nerve and retinal nerve fiber layer. Nineteen of these also had OCT of the macula during periods of acute, subacute, or recurrent papilledema and were evaluated in detail for this report.

Results  Seven patients had OCT evidence of subretinal fluid involving the macula. All had some reduction in visual acuity. The subretinal fluid appeared to arise from the peripapillary region, and all showed some improvement in central vision as the fluid resolved.

Conclusions  Subretinal fluid accumulations can cause decreased visual acuity in patients with papilledema. Optical coherence tomography can demonstrate subretinal fluid and can be used to follow the course of this important visual complication of papilledema.

From the Departments of Ophthalmology (Drs Hoye, Berrocal, Hedges, and Amaro-Quireza) and Neurology (Dr Hedges), Tufts University School of Medicine, and The New England Medical Center, Boston, Mass.

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