This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on ISI (40)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Ophthalmology, Other  • Alert me on articles by topic

Steven A. Madreperla, MD, PhD

Arch Ophthalmol. 2001;119:1606-1610.

Objective  To describe a new treatment for vision loss caused by subretinal fluid associated with circumscribed choroidal hemangioma.

Methods  Three patients were treated with photodynamic therapy using verteporfin for injection (Visudyne; QLT Phototherapeutics Inc, Vancouver, British Columbia). All patients had pretreatment and posttreatment fluorescein angiography and ultrasonography. Treatment parameters used were verteporfin, 6 mg/m², and laser light at 689 nm delivered at 50 J/cm² with an intensity of 600 mW/cm² for 83 seconds.

Results  All patients had complete resolution of subretinal fluid within 2 weeks of treatment. Fluorescein angiography performed 2 to 4 weeks after treatment showed absence of tumor leakage. All eyes had reduced tumor thickness or complete flattening. Visual acuity was improved in each eye. Average follow-up was 5.3 months. No complications were noted.

Conclusion  Photodynamic therapy with verteporfin is effective in eliminating subretinal fluid and improving vision in patients with circumscribed choroidal hemangioma.

From the Retina Associates of New Jersey, Teaneck. The author has no proprietary interest in this research.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Photodynamic therapy for exudative hamartoma in tuberous sclerosis.
Mennel et al.
Arch Ophthalmol 2006;124:597-599.
FULL TEXT  

Three Cases of Large Retinal Capillary Hemangiomas Treated With Verteporfin and Photodynamic Therapy
Aaberg et al.
Arch Ophthalmol 2005;123:328-332.
ABSTRACT | FULL TEXT  

Palladium 103 (103Pd) Plaque Radiation Therapy for Circumscribed Choroidal Hemangioma With Retinal Detachment
Aizman et al.
Arch Ophthalmol 2004;122:1652-1656.
ABSTRACT | FULL TEXT  

Photodynamic therapy of circumscribed choroidal haemangioma
Singh et al.
Br. J. Ophthalmol. 2004;88:1414-1418.
ABSTRACT | FULL TEXT  

Photodynamic therapy using verteporfin in circumscribed choroidal haemangioma
Jurklies et al.
Br. J. Ophthalmol. 2003;87:84-89.
ABSTRACT | FULL TEXT  

Photodynamic Therapy for Choroidal Hemangioma Associated With Serous Retinal Detachment
Robertson
Arch Ophthalmol 2002;120:1155-1161.
ABSTRACT | FULL TEXT