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John S. Stahl, MD, PhD; Lea Averbuch-Heller, MD; R. John Leigh, MD

Arch Ophthalmol. 2000;118:544-549.

Traditionally, acquired forms of nystagmus have been classified in descriptive terms based on their clinical features and recorded waveforms. In the past 20 years, the mechanisms of several major forms of nystagmus have been elucidated; animal and mathematical models for these ocular oscillations have been developed. These advances, which owe much to modern anatomical, physiological, and pharmacological techniques, have enhanced the diagnostic value of nystagmus and provide the basis for developing rational therapy.

From the Departments of Neurology (Drs Stahl and Leigh), Neuroscience (Dr Leigh), and Biomedical Engineering (Dr Leigh), Department of Veterans Affairs Medical Center and University Hospitals, Case Western Reserve University, Cleveland, Ohio; and the Departments of Neurology and Ophthalmology, Rabin Medical Center, Tel Aviv, Israel (Dr Averbuch-Heller).

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