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Raymond R. Margherio, MD; Alan R. Margherio, MD; George A. Williams, MD; David R. Chow, MD; Michael J. Banach, MD

Arch Ophthalmol. 2000;118:495-498.

Objective  To evaluate the efficacy of perifoveal tissue dissection (PTD) on patients undergoing pars plana vitrectomy for idiopathic macular holes of less than 1-year's duration.

Methods  Pars plana core vitrectomy was performed on 107 eyes of 104 consecutive patients with acute idiopathic macular holes. One cohort had routine PTD. In the other cohort, no attempt was made to strip preretinal tissue. Follow-up was longer than 6 months (follow-up range, 6 to 36 months).

Results  Overall, 95 (89%) of all macular holes were closed. Visual acuity improved 2 lines or more of the Snellen letter chart in 91 eyes (85%). A postoperative visual acuity of 20/50 or better was achieved in 79 eyes (74%). A transient increase in intraocular pressure (30 mm Hg) developed in 25 eyes (23.4%). In 6 eyes (5.6%) a retinal detachment developed. One eye had retinal pigment epithelial changes and 1 patient reported peripheral field loss. No statistically significant differences were noted between eyes having PTD and those without PTD for any outcome measure.

Conclusion  In this series, no beneficial or adverse effect could be demonstrated by performing PTD in eyes undergoing pars plana core vitrectomy for acute idiopathic macular holes.

From the Associated Retinal Consultants and William Beaumont Hospital, Royal Oak, Mich (Drs R. R. Margherio and Williams); Eye Research Institute, Oakland University, Rochester, Mich (Drs R. R. Margherio and Williams); Associated Retinal Consultants PC and Butterworth Hospital, Grand Rapids, Mich (Dr A. R. Margherio); Michigan State University College of Human Medicine, Lansing (Dr A. R. Margherio); and the Beaumont Eye Institute, Royal Oak, Mich, and Oakland University, Eye Research Institute, Rochester, Mich (Drs Chow and Banach).

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