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Gayle C. Williams, MD, PhD; Eric Holz, MD; Andrew G. Lee, MD; Ramon L. Font, MD

Arch Ophthalmol. 2000;118:278-280.

A 59-year-old man with a history of mycosis fungoides developed loss of visual acuity and visual field in the left eye. Epiretinal lesions were present in the right eye and multifocal choroidal lesions, optic disc edema, and vitritis were present in the left eye. A diagnostic vitrectomy was performed and cytologic examination of the vitreous confirmed the diagnosis of T-cell lymphoproliferative disorder. Systemic and intrathecal chemotherapy resulted in marked improvement in ocular signs and symptoms. At last follow-up, the patient was found to have improved visual acuity in the left eye; however, significant worsening of his systemic condition developed and he died shortly thereafter.

From the Departments of Ophthalmology (Drs Williams, Holz, Lee, and Font), Neurology and Neurosurgery (Dr Lee), and Pathology (Dr Font), Baylor College of Medicine; and the Department of Neurosurgery, M. D. Anderson Cancer Center, the University of Texas (Dr Lee); Houston, Tex.

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