This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on ISI (11)  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Surgery  • Laser Surgery  • Glaucoma  • Laser Surgery  • Alert me on articles by topic

Jayne Ge, MD; Martin Wand, MD; Robert Chiang, MD; Augusto Paranhos, MD; M. Bruce Shields, MD

Arch Ophthalmol. 2000;118:1334-1337.

Objective  To study the long-term effect of Nd:YAG capsulotomy on intraocular pressure (IOP).

Methods  We reviewed the records of patients with bilateral pseudophakia who received Nd:YAG capsulotomy in only 1 eye. Using the Wilcoxon rank sum test, we compared the mean change in IOP in eyes before and after capsulotomy with that of the noncapsulotomy eyes at corresponding time intervals. Using multiple regression tests, we analyzed the factors significantly associated with postcapsulotomy long-term IOP increases.

Results  The study included 100 patients who were followed up for a median of 1.5 years after capsulotomy. The mean ± SD age of the study group was 76±7 years, and 37 patients had glaucoma. The changes in IOP in the eyes treated with capsulotomy were significantly higher than those in noncapsulotomy eyes at each time interval following capsulotomy. The long-term IOP increase was significantly associated with the IOP increase measured 1 hour after the capsulotomy (P = .001). Patients with glaucoma were more likely to require long-term additional glaucoma medication than were nonglaucoma patients to require initial glaucoma therapy after the capsulotomy (P = .002).

Conclusion  After Nd:YAG capsulotomy, long-term IOP is often elevated above precapsulotomy baselines, especially in glaucoma patients or patients who experience a significant IOP increase within hours after the capsulotomy.

From the Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Conn (Drs Ge, Chiang, Paranhos, and Shields); and the Departments of Ophthalmology, University of Connecticut School of Medicine, Farmington, and Hartford Hospital, Hartford, Conn (Dr Wand).

RELATED ARTICLE

Archives of Ophthalmology Reader's Choice: Continuing Medical Education
Arch Ophthalmol. 2000;118(10):1472-1473.
FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Intraocular pressure control after Nd:YAG laser posterior capsulotomy in eyes with glaucoma
Lin et al.
Br. J. Ophthalmol. 2008;92:337-339.
ABSTRACT | FULL TEXT  

More than just an ocular solution
Pekdemir et al.
Emerg. Med. J. 2005;22:753-754.
ABSTRACT | FULL TEXT