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Probability of Filtration Surgery in Patients With Open-angle Glaucoma
Matthew G. Hattenhauer, MD;
Douglas H. Johnson, MD;
Helen H. Ing, RN;
David O. Hodge, MS;
Linda C. Butterfield, MD;
David C. Herman, MD;
Darryl T. Gray, MD, ScD
Arch Ophthalmol. 1999;117:1211-1215.
Objective To investigate the probability of undergoing filtration surgery in either 1 or both eyes in patients in whom open-angle glaucoma was newly diagnosed.
Methods and Design A retrospective community-based study of 295 residents of Olmsted County, Minnesota, in whom open-angle glaucoma was newly diagnosed between January 1, 1965, and December 31, 1980, was performed. Kaplan-Meier methods were used to estimate the cumulative probability of undergoing filtration surgery during a 20-year period.
Results At 20 years of follow-up, the Kaplan-Meier cumulative probability of undergoing filtration surgery in at least 1 eye was estimated to be 23% (95% confidence interval, 16%-30%), and in both eyes the estimate was 12% (95% confidence interval, 6%-17%). Patients with optic nerve damage at the time of diagnosis were more likely to undergo surgery than patients with elevated intraocular pressure but no damage (1 eye, 39% vs 15%; both eyes, 27% vs 5%).
Conclusion This retrospective study of a white population newly diagnosed as having and treated for open-angle glaucoma indicates that while most patients did not undergo filtration surgery in the course of glaucoma therapy, at least one third of those with glaucomatous damage at the time of diagnosis underwent filtration surgery.
From the Departments of Ophthalmology (Drs Hattenhauer, Johnson, and Herman and Ms Ing) and Health Sciences Research (Mr Hodge and Dr Gray), Mayo Clinic and Mayo Foundation; and Department of Ophthalmology (Dr Butterfield), Olmsted Medical Center, Rochester, Minn. Dr Gray is now with the Department of Health Services at the University of Washington School of Public Health and Community Medicine, Seattle.
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