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Peter J. Breingan, MD; Kohji Esaki, MD; Hiroshi Ishikawa, MD; Jeffrey M. Liebmann, MD; David S. Greenfield, MD; Robert Ritch, MD

Arch Ophthalmol. 1999;117:325-328.

Objective  To evaluate changes in anterior segment anatomy after laser iridotomy for pigment dispersion syndrome.

Methods  Ultrasound biomicroscopy was performed on 7 eyes of 7 untreated patients with reverse pupillary block and pigment dispersion syndrome. A radially oriented image with the probe perpendicular to the eye in the superior meridian was obtained before and at least 1 week after laser iridotomy in each eye. We assessed changes in angle recess area and iris-lens contact distance.

Results  Mean ± SD patient age was 31.3 ± 5.7 years and mean±SD refractive error was -5.0 ± 3.9 diopters. Angle recess area (mean±SD, 0.78 ± 0.28 vs 0.35 ± 0.11 mm²; P=.001, paired t test) and iris-lens contact distance (2.05 ± 0.28 vs 0.79 ± 0.13 mm; P<.001) decreased following iridotomy. Central anterior chamber depth did not change.

Conclusion  Flattening of the iris following laser iridotomy for pigment dispersion syndrome causes a decrease in iris-lens contact and angle width while lens position remains constant.

From the Departments of Ophthalmology, New York Eye and Ear Infirmary, New York (Drs Breingan, Esaki, Ishikawa, Liebmann, Greenfield, and Ritch); and New York Medical College, Valhalla (Drs Ishikawa, Liebmann, Greenfield, and Ritch). Dr Esaki is now affiliated with the Department of Ophthalmology, Mie University School of Medicine, Mie, Japan. Dr Greenfield is now affiliated with Bascom-Palmer Eye Institute, Miami, Fla. The authors have no financial interest in any device described in this article.

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