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Parry-Romberg Syndrome Associated With Intracranial Vascular Malformations
Arch Ophthalmol. 1998;116:1235-1237.
We describe a 23-year-old woman with iridocyclitis, enophthalmos, facial hemiatrophy, and transient numbness of her contralateral upper and lower extremities. The patient was found to have white matter densities in the right hemisphere in magnetic resonance T2-weighted images and vascular malformations involving right vertebral, right carotid, and right anterior cerebral arteries. Histopathologic evaluation of a biopsy specimen of anterior orbital fat and lacrimal gland revealed fibrosis and chronic inflammation. These findings were consistent with the diagnosis of progressive facial hemiatrophy (Parry-Romberg syndrome) in association with iridocyclitis and intracranial vascular malformations.
Anita I. Miedziak, MD;
Mary Stefanyszyn, MD;
Joseph Flanagan, MD;
Ralph C. Eagle, Jr, MD
From the Oculoplastics Service (Drs Miedziak, Stefanyszyn, and Flanagan) and the Department of Pathology (Dr Eagle), Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pa.
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