This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (9)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Ophthalmology, Other  • Alert me on articles by topic  Social Bookmarking   What's this?

Arch Ophthalmol. 1998;116:674-677.

Objective  To describe ocular findings in 2 patients with disseminated coccidioidomycosis diagnosed by skin biopsy.

Methods  The clinical and histopathologic findings of the 2 patients were reviewed retrospectively.

Results  One patient had a unilateral, granulomatous iridocyclitis with multiple iris nodules and a large vascularized anterior chamber mass, in the setting of pulmonary, cutaneous, and skeletal infection by Coccidioides immitis. The second patient developed papilledema and multifocal chorioretinitis accompanied by pulmonary, cutaneous, and meningeal C immitis infection. In each case, examination of the skin biopsy specimen revealed C immitis spherules. Treatments included local and systemic amphotericin B and oral fluconazole.

Conclusions  Although rare, intraocular involvement can occur in the setting of disseminated coccidioidomycosis. A thorough systemic evaluation and biopsy of suspicious skin lesions can aid in the diagnosis.

Emmett T. Cunningham, Jr, MD, PhD, MPH; Stuart R. Seiff, MD; Timothy G. Berger, MD; Paul E. Lizotte, DO; Edward L. Howes, Jr; Jonathan C. Horton, MD, PhD
From The Francis I. Proctor Foundation (Dr Cunningham); and the Departments of Ophthalmology (Drs Cunningham, Seiff, and Horton and Mr Howes), Dermatology (Dr Berger), Nuclear Medicine (Dr Lizotte), and Pathology (Mr Howes), University of California, San Francisco, School of Medicine.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Retinal seeding from anterior segment coccidioidomycosis after vitrectomy
Mondino et al.
Br J Ophthalmol 2007;91:837-839.
FULL TEXT  

Current Perspectives on Ophthalmic Mycoses
Thomas
Clin. Microbiol. Rev. 2003;16:730-797.
ABSTRACT | FULL TEXT  

Iris nodules associated with infectious uveitis
Myers et al.
Br J Ophthalmol 2002;86:969-974.
ABSTRACT | FULL TEXT  

Fungal and Parasitic Infections of the Eye
Klotz et al.
Clin. Microbiol. Rev. 2000;13:662-685.
ABSTRACT | FULL TEXT