This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (61)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Cataracts/ Lens  • Macular Degeneration  • Alert me on articles by topic  Social Bookmarking   What's this?

Ronald Klein, MD, MPH; Barbara E. K. Klein, MD, MPH; Susan C. Jensen, MS; Karen J. Cruickshanks, PhD

Arch Ophthalmol. 1998;116:506-513.

Objective  To examine the association between ocular factors and the incidence and progression of age-related maculopathy.

Participants  A population of 3684 adults (43-86 years of age at baseline) living in Beaver Dam, Wis, studied at baseline and 5 years later.

Methods  Standardized protocols for refraction and determination of iris color, administration of a questionnaire, and slitlamp and retroillumination photographs of the lenses to determine cataract type and stereoscopic color fundus photographs to determine presence and severity of age-related maculopathy. Standard univariate and multivariate analyses were performed.

Main Outcome Measures  Incidence and progression of age-related maculopathy.

Results  After controlling for age, eyes that had undergone cataract surgery before baseline were more likely to have progression of age-related maculopathy (odds ratio, 2.71; 95% confidence interval [CI], 1.69-4.35) and to develop signs of late age-related maculopathy (odds ratio, 2.80; 95% CI, 1.03-7.63) than were eyes that were phakic at baseline. These relationships remained after controlling for other risk factors in multivariate analyses. There was no relationship of nuclear cataract, cortical cataract, or iris color to the incidence and progression of age-related maculopathy.

Conclusion  These findings indicate a relationship between cataract surgery and increased risk of progression of age-related maculopathy.

From the Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Cataract Surgery and the Risk of Aging Macula Disorder: The Rotterdam Study
Ho et al.
IOVS 2008;49:4795-4800.
ABSTRACT | FULL TEXT  

Age-Related Macular Degeneration
Jager et al.
NEJM 2008;358:2606-2617.
FULL TEXT  

Estrogen Receptor Alpha and Matrix Metalloproteinase 2 Polymorphisms and Age-related Maculopathy in Older Women
Seitzman et al.
Am J Epidemiol 2008;167:1217-1225.
ABSTRACT | FULL TEXT  

What can patients expect from cataract surgery?
BOLLINGER and LANGSTON
Cleveland Clinic Journal of Medicine 2008;75:193-200.
ABSTRACT | FULL TEXT  

Phacoemulsification Does Not Induce Neovascular Age-Related Macular Degeneration
Baatz et al.
IOVS 2008;49:1079-1083.
ABSTRACT | FULL TEXT  

Is Pseudophakia a Risk Factor for Neovascular Age-Related Macular Degeneration?
Sutter et al.
IOVS 2007;48:1472-1475.
ABSTRACT | FULL TEXT  

Associated factors for age related maculopathy in the adult population in China: the Beijing eye study
Xu et al.
Br J Ophthalmol 2006;90:1087-1090.
ABSTRACT | FULL TEXT  

Risk Factors for Age-Related Macular Degeneration: Findings from the Andhra Pradesh Eye Disease Study in South India
Krishnaiah et al.
IOVS 2005;46:4442-4449.
ABSTRACT | FULL TEXT  

Relationship between Refraction and Prevalent as well as Incident Age-Related Maculopathy: The Rotterdam Study
Ikram et al.
IOVS 2003;44:3778-3782.
ABSTRACT | FULL TEXT  

Risk factors for age related maculopathy in a Japanese population: the Hisayama study
Miyazaki et al.
Br J Ophthalmol 2003;87:469-472.
ABSTRACT | FULL TEXT  

The Association of Cataract and Cataract Surgery With the Long-term Incidence of Age-Related Maculopathy: The Beaver Dam Eye Study
Klein et al.
Arch Ophthalmol 2002;120:1551-1558.
ABSTRACT | FULL TEXT  

Refractive Errors and 10-Year Incidence of Age-Related Maculopathy
Wong et al.
IOVS 2002;43:2869-2873.
ABSTRACT | FULL TEXT  

Risk Factors for Age-Related Maculopathy: The Visual Impairment Project
McCarty et al.
Arch Ophthalmol 2001;119:1455-1462.
ABSTRACT | FULL TEXT  

Sunlight and the 5-Year Incidence of Early Age-Related Maculopathy: The Beaver Dam Eye Study
Cruickshanks et al.
Arch Ophthalmol 2001;119:246-250.
ABSTRACT | FULL TEXT  

Cataract surgery in patients with cataract and age related macular degeneration: do the benefits outweigh the risks?
WONG
Br J Ophthalmol 2000;84:1337-1338.
FULL TEXT  

Macular pigment and age related macular degeneration
BEATTY et al.
Br J Ophthalmol 1999;83:867-877.
FULL TEXT  

Do patients with age related maculopathy and cataract benefit from cataract surgery?
AMBRECHT et al.
Br J Ophthalmol 1999;83:252b-252.
FULL TEXT  

Relationship of Ocular Factors to the Incidence of Age-Related Maculopathy
LeClaire et al.
Arch Ophthalmol 1998;116:1404-1405.
FULL TEXT