 |
 |

Factors Associated With Intraocular Pressure-Induced Acute Visual Field Depression
John R. Trible, MD;
Douglas R. Anderson, MD
Arch Ophthalmol. 1997;115(12):1523-1527.
Abstract
 |  |
Objective To determine the factors associated with visual field depression produced by artificial elevation of intraocular pressure (IOP).
Methods The visual threshold was determined at 26 locations in the central visual field at a spontaneous IOP, at 30 mm Hg, at 40 mm Hg, and at the IOP immediately following release of the suction cup used to elevate the IOP artificially in 33 subjects with and without glaucoma. The net decrease in threshold sensitivity at each IOP level relative to sensitivity obtained at the spontaneous IOP was calculated (acute visual field depression).
Results Factors potentially influencing the acute visual field depression between subjects were determined with stepwise regression. The reciprocal of ocular perfusion pressure, a clinical measure, was strongly correlated with acute visual field depression (dependent variable), particularly at 40 mm Hg (at 30 mm Hg, r=0.412, P=.02, n=32; and at 40 mm Hg, r=0.813, P<.001, n=33). When a second variable, the diagnosis of glaucoma, was included in the regression at 40 mm Hg, it contributed significantly (partial r=0.650, P<.001, n=26). The degree of glaucomatous damage (vertical cup-disc ratio or baseline Humphrey 24-2 visual field mean deviation) failed to correlate with acute field depression, with or without correction for ocular perfusion pressure.
Conclusions The elevation of IOP produces acute, reversible visual field depression. This depression is largely dependent on the subject's ocular perfusion pressure. The degree of depression is greater in those with glaucoma but is not strictly related to the degree of glaucomatous damage.
Author Affiliations
From the Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, Fla. Dr Trible is now with The Eye Institute, Medical College of Wisconsin, Milwaukee.
CiteULike Connotea Del.icio.us Digg Reddit Technorati Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Intraocular Pressure and Calculated Diastolic Ocular Perfusion Pressure during Three Simulated Steps of Phacoemulsification In Vivo
Zhao et al.
IOVS 2009;50:2927-2931.
ABSTRACT
| FULL TEXT
The Gradient of Retinal Functional Changes during Acute Intraocular Pressure Elevation
Bui et al.
IOVS 2005;46:202-213.
ABSTRACT
| FULL TEXT
Fellow Eye Prognosis in Patients With Severe Visual Field Loss in 1 Eye From Chronic Open-Angle Glaucoma
Chen and Bhandari
Arch Ophthalmol 2000;118:473-478.
ABSTRACT
| FULL TEXT
|