This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (4)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Multiple Viruses in Pathogenesis

Murat Tunc, MD; Martha L. Simmons, MD, PhD; Devron H. Char, MD; Brian Herndier, MD, PhD

Arch Ophthalmol. 1997;115(11):1464-1466.

Abstract
A 36-year-old patient with the acquired immunodeficiency syndrome sought care because of an upper eyelid lesion that dramatically increased in size. The histopathologic examination revealed a high-grade diffuse large cell non-Hodgkin lymphoma in continuity with a Kaposi sarcoma. In situ hybridization revealed Epstein-Barr virus in the large cell lymphoma and Kaposi sarcoma-associated herpesvirus in the Kaposi sarcoma lesion. This collision tumor is an unusual presentation of 2 malignant neoplasms in a patient with acquired immunodeficiency syndrome, with in situ hybridization evidence of Epstein-Barr virus and Kaposi sarcoma-associated herpesvirus in the lesion.

Author Affiliations
From the Departments of Ophthalmology (Drs Tunc and Char), Pathology (Drs Simmons and Herndier), and Radiation Oncology (Dr Char), University of California, San Francisco, and the Francis I. Proctor Foundation, San Francisco (Dr Char).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Acute Myeloid Leukemia Manifesting Initially as a Conjunctival Mass in a Patient With Acquired Immunodeficiency Syndrome
Nau et al.
Arch Ophthalmol 2002;120:1741-1742.
FULL TEXT