This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (16)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Ben J. Glasgow, MD; Robert E. Engstrom, Jr, MD; Gary N. Holland, MD; Allen E. Kreiger, MD; Michael G. Wool, MD

Arch Ophthalmol. 1996;114(7):873-877.

Abstract
A 51-year-old man with acquired immunodeficiency syndrome and cytomegalovirus retinitis had bilateral endogenous fungal endophthalmitis. Cultures yielded Fusarium species. Histopathologic examination showed a severe necrotizing acute and granulomatous reaction, with numerous fungal elements in the retina and uveal tract. Fungal elements were seen in the lens, sclera, and emissarial vessels. Angiopathic infiltration by fungus and widespread thrombosis produced retinal and choroidal infarction. In some areas, fungal infection coexisted with cytomegalovirus retinitis. The bilateral distribution suggests hematogenous seeding of the eyes. The eye findings were the first clinically apparent manifestations of fungal disease in this patient.

Author Affiliations
From The Jules Stein Eye Institute (Drs Glasgow, Engstrom, Holland, Kreiger, and Wool), the Ocular Inflammatory Disease Center (Dr Holland), and the Departments of Ophthalmology (Drs Glasgow, Engstrom, Holland, and Kreiger), Pathology (Drs Glasgow and Wool), and Medicine (Dr Wool), University of California-Los Angeles School of Medicine. Dr Engstrom is a David May II fellow in vitreoretinal diseases and surgery.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Disseminated Fusarium Infection Presenting as Bilateral Endogenous Endophthalmitis in a Patient With Acute Myeloid Leukemia
Rezai et al.
Arch Ophthalmol 2005;123:702-703.
FULL TEXT  

Current Perspectives on Ophthalmic Mycoses
Thomas
Clin. Microbiol. Rev. 2003;16:730-797.
ABSTRACT | FULL TEXT  

Fungal and Parasitic Infections of the Eye
Klotz et al.
Clin. Microbiol. Rev. 2000;13:662-685.
ABSTRACT | FULL TEXT  

Mixed Infection Caused by Two Species of Fusarium in a Human Immunodeficiency Virus-Positive Patient
Guarro et al.
J. Clin. Microbiol. 2000;38:3460-3462.
ABSTRACT | FULL TEXT  

Acquired Immunodeficiency Syndrome and the Eye--1996
Jabs
Arch Ophthalmol 1996;114:863-866.
ABSTRACT