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Tom S. Chang, MD; Sandra Frazier Byrne; J. Donald M. Gass, MD; J. Randall Hughes; Robert N. Johnson, MD; Timothy G. Murray, MD

Arch Ophthalmol. 1996;114(6):669-675.

Abstract
Background
Benign reactive lymphoid hyperplasia is an uncommon uveal tumor. Misdiagnosis may lead to unnecessary enucleations. Clinical evaluation alone is usually not sufficient to diagnose this tumor.

Objective
To evaluate the utility of standardized echography in the recognition of this disease.

Methods
Retrospective review of the medical and echographic records of 6 patients with choroidal involvement of benign reactive lymphoid hyperplasia.

Results
Extraocular episcleral lymphoid nodules were present in 5 of the 6 patients and were usually seen as a late manifestation of the disease. Two patients had repeated echography after treatment of the tumor and showed marked regression of the episcleral nodules.

Conclusions
A combination of clinical and echographic findings can assist in the accurate diagnosis of this rare uveal tumor. The presence of episcleral nodules on standardized echography supports the diagnosis.

Author Affiliations
From the Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami (Fla). Dr Chang is now with the Department of Ophthalmology, University of British Columbia, Vancouver. Dr Johnson is now in private practice in San Francisco, Calif.

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