Microscopic polyangiitis with ocular involvement
J. C. Caster, D. J. Shetlar, M. A. Pappolla and R. W. Yee
Department of Ophthalmology, University of Texas Houston Health Science Center, USA.
Microscopic polyangiitis is an exclusively small-vessel (arterioles,
capillaries, or venules) vasculitis that primarily involves the kidney and
often involves the lungs, skin, or nervous system. Characteristic features
include focal segmental glomerulonephritis, nongranulomatous necrotizing
vasculitis, and serum positive for perinuclear-staining antineutrophil
cytoplasmic antibodies (P-ANCA). We report a case of microscopic
polyangiitis with previously unreported eyelid and conjunctival
manifestations that responded well to immunosuppressive therapy.
