Ocular tumoral calcinosis. A clinicopathologic study
F. Ghanchi, A. Ramsay, S. Coupland, D. Barr and W. R. Lee
Tennent Institute of Ophthalmology, Western Infirmary, Glasgow, Scotland.
Tumoral calcinosis is a rare systemic disorder characterized by
para-articular ectopic soft-tissue calcification. This case report
describes the ophthalmic features (palpebral conjunctival calcific nodules,
the white limbal girdle of Vogt, disc drusen, and angioid streaks) in a
38-year-old Asian woman who had tumoral calcinosis associated with
hyperphosphatemia. A morphologic study of the calcified nodules on the
palpebral conjunctiva disclosed deposition of hydroxyapatite crystals in an
extracellular matrix (deposit) containing alcianophilic
mucopolysaccharides. Excision of the eyelid nodules was not followed by
recurrence.
