Cutaneous malignant melanoma with diffuse intraocular metastases
C. B. Bowman, D. Guber, C. H. Brown 3rd and V. T. Curtin
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Fla.
A 63-year-old man with a history of cutaneous melanoma and a 3-month
history of visual loss in his right eye presented with marked pigmentation
of the anterior-segment structures, including trabecular meshwork, iris,
and lens surface, with pigment dispersion in the aqueous and anterior
vitreous in the right eye. Clinical examination and echography showed no
evidence of an intraocular tumor although metastatic melanoma was
suspected. Pathologic examination revealed numerous heavily pigmented
melanoma cells throughout the anterior segment of the eye, mainly
concentrated in the anterior vitreous near the ciliary body. No discrete
tumor was found on multiple sections through the globe.
