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Association With Endocrine and Central Nervous System Anomalies

H. Sprague Eustis, MD; Marc R. Sanders, MD; Teresa Zimmerman, MD

Arch Ophthalmol. 1994;112(2):204-207.

Abstract
Objective
To identify morning glory syndrome, an uncommon optic disc anomaly. Generally, it is an isolated ocular abnormality; however, some cranial facial and neurologic associations have been reported.

Patients
We herein report two patients with morning glory syndrome and associated pituitary dwarfism. In one patient, the pituitary insufficiency was secondary to compression of the pituitary gland by a basal encephalocele; in the second patient, causative factors were not identified.

Conclusions
Patients with morning glory syndrome should have a complete general physical examination and growth evaluation so that early recognition and treatment of the patient with pituitary dwarfism can occur.

Author Affiliations
From the Departments of Ophthalmology (Drs Eustis and Sanders) and Pediatrics (Drs Eustis and Zimmerman), Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, La.

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