Multifocal fibrosclerosis. Report of a case of bilateral idiopathic sclerosing pseudotumor and retroperitoneal fibrosis
M. R. Levine, L. Kaye, S. Mair and J. Bates
Division of Ophthalmology, Mt Sinai Medical Center, Cleveland, Ohio.
We describe a 56-year-old white man who presented with gradual and
progressive visual loss and subsequent hypertension and pedal edema. A
computed tomographic scan of the orbits showed bilateral diffuse
retrobulbar masses, and an abdominal computed tomographic scan showed a
diffuse retroperitoneal mass invading the aorta, ureters, and inferior vena
cava. Biopsies of the orbit and abdomen confirmed a heterogeneous cell
population and marked fibrosis consistent with a sclerosing inflammatory
process. Bilateral sclerosing orbital inflammatory disease should cue the
physician to suspect coexisting systemic disease. This report is the fourth
to document bilateral sclerosing orbital inflammatory disease and the
second to have obtained biopsies of the orbit and abdomen showing
histologic similarities.
