Miliary toxoplasmic retinitis in acquired immunodeficiency syndrome
B. B. Berger, C. E. Egwuagu, W. R. Freeman and C. A. Wiley
University of Texas Health Sciences Center, San Antonio.
A unique pattern of bilateral miliary retinitis due to ocular toxoplasmosis
developed in a patient in the late stages of acquired immunodeficiency
syndrome. Results of serologic tests for toxoplasmosis remained negative
throughout the clinical course of his ocular disease. The retinitis was
unresponsive to a brief course of anti-toxoplasmosis therapy. At autopsy,
the histopathologic material was consistent with toxoplasmic retinitis and
the DNA polymerase chain reaction was positive for toxoplasmosis.
Recognition of this pattern of retinitis is important in the appropriate
treatment of immunosuppressed patients with retinitis.
