Baseline visual field profile of optic neuritis. The experience of the optic neuritis treatment trial. Optic Neuritis Study Group
J. L. Keltner, C. A. Johnson, J. O. Spurr and R. W. Beck
Department of Ophthalmology, University of California, Davis 95616.
The purpose of the present study was to determine the baseline visual field
characteristics in 448 patients with acute optic neuritis who were entered
into the Optic Neuritis Treatment Trial. The severity and pattern of visual
field loss in both the affected and fellow eyes were classified. For
affected eyes, diffuse visual field loss was present in 48.2% of eyes,
central or centrocecal scotoma was present in 8.3% of eyes, altitudinal or
other nerve-fiber bundle-type defects were present in 20.1% of eyes, and a
variety of other defects were present in 23.4% of eyes. Visual field
involvement was present in the fellow eye at baseline in 308 (68.8%) of the
448 patients. Evidence of a chiasmal or retrochiasmal visual field defect
was present in 2.9% of the patients. Since a wide variety of visual field
defects can occur with an acute attack of optic neuritis, the pattern of
visual field loss is of limited utility in distinguishing optic neuritis
from ischemic optic neuropathy and other optic nerve disorders.
Asymptomatic visual field defects in the fellow eye are common.
The Optic Neuritis Treatment Trial: A Definitive Answer and Profound Impact With Unexpected Results
Volpe
Arch Ophthalmol 2008;126:996-999.
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Huang et al.
IOVS 2008;49:917-923.
ABSTRACT
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Neuro-Ophthalmology for Neuroradiologists
Jacobs and Galetta
Am. J. Neuroradiol. 2007;28:3-8.
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Leber's Hereditary Optic Neuropathy with Childhood Onset
Barboni et al.
IOVS 2006;47:5303-5309.
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Multifocal visual evoked potential latency analysis: predicting progression to multiple sclerosis.
Fraser et al.
Arch Neurol 2006;63:847-850.
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Clinical practice. Optic neuritis.
Balcer
NEJM 2006;354:1273-1280.
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Infliximab-Associated Retrobulbar Optic Neuritis
Mejico
Arch Ophthalmol 2004;122:793-794.
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Spatial vision in visually asymptomatic subjects at high risk for multiple sclerosis
Frisen
J. Neurol. Neurosurg. Psychiatry 2003;74:1145-1147.
ABSTRACT
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Classification of Visual Field Abnormalities in the Ocular Hypertension Treatment Study
Keltner et al.
Arch Ophthalmol 2003;121:643-650.
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Variation of visual evoked potential delay to stimulation of central, nasal, and temporal regions of the macula in optic neuritis
Rinalduzzi et al.
J. Neurol. Neurosurg. Psychiatry 2001;70:28-35.
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Use of a portable head mounted perimetry system to assess bedside visual fields
Hollander et al.
Br. J. Ophthalmol. 2000;84:1185-1190.
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Practice parameter: The role of corticosteroids in the management of acute monosymptomatic optic neuritis: Report of the Quality Standards Subcommittee of the American Academy of Neurology
Kaufman et al.
Neurology 2000;54:2039-2044.
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Long- and Short-term Variability of Automated Perimetry Results in Patients With Optic Neuritis and Healthy Subjects
Wall et al.
Arch Ophthalmol 1998;116:53-61.
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