Incidence of ulcerative keratitis in a defined population from 1950 through 1988
J. C. Erie, M. P. Nevitt, D. O. Hodge and D. J. Ballard
Department of Ophthalmology, Mayo Clinic, Rochester, Minn.
OBJECTIVE: To determine the incidence of ulcerative keratitis and to assess
trends in risk factors leading to ulcerative keratitis. DESIGN:
Retrospective incidence cohort study. SETTING: General community. PATIENTS:
Population-based sample of residents of Olmsted County, Minnesota, in the
39-year period between 1950 and 1988. MAIN OUTCOME MEASURE: Cases of
ulcerative keratitis. RESULTS: One hundred forty-one cases of ulcerative
keratitis were diagnosed among 131 residents (64 men and 67 women) of
Olmsted County. The mean annual age-adjusted incidence per 100,000 people
was 5.3 (95% confidence interval, 4.4 to 6.2). A 435% increase in the
incidence of ulcerative keratitis was observed in Olmsted County residents
from the 1950s (2.5 per 100,000 people) to the 1980s (11.0 per 100,000
people) (P = .001). The cases of ulcerative keratitis associated with
contact lens wear increased from 0% in the 1950s and 1960s to 32% in the
1970s and 52% in the 1980s. CONCLUSION: The incidence of ulcerative
keratitis has increased significantly in this community. Contact lens wear
was the most important risk factor for the development of ulcerative
keratitis during the last decade.
Initial therapy for suppurative microbial keratitis in Iraq
Al-Shakarchi
Br. J. Ophthalmol. 2007;91:1583-1587.
ABSTRACT
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Corneal ulceration in south-east Asia III: prevention of fungal keratitis at the village level in south India using topical antibiotics
Srinivasan et al.
Br. J. Ophthalmol. 2006;90:1472-1475.
ABSTRACT
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Fusarium--A New Culprit in the Contact Lens Case
Margolis and Whitcher
JAMA 2006;296:985-987.
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Hypoxia Increases Corneal Cell Expression of CFTR Leading to Increased Pseudomonas aeruginosa Binding, Internalization, and Initiation of Inflammation
Zaidi et al.
IOVS 2004;45:4066-4074.
ABSTRACT
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Influence of Fluoroquinolone Susceptibility on the Therapeutic Response of Fluoroquinolone-Treated Bacterial Keratitis
Wilhelmus et al.
Arch Ophthalmol 2003;121:1229-1233.
ABSTRACT
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Simplifying Collection of Corneal Specimens in Cases of Suspected Bacterial Keratitis
Kaye et al.
J. Clin. Microbiol. 2003;41:3192-3197.
ABSTRACT
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Microbial keratitis
Jeng and McLeod
Br. J. Ophthalmol. 2003;87:805-806.
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Bacterial keratitis: predisposing factors, clinical and microbiological review of 300 cases
Bourcier et al.
Br. J. Ophthalmol. 2003;87:834-838.
ABSTRACT
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Herpes Zoster Ophthalmicus in Olmsted County, Minnesota: Have Systemic Antivirals Made a Difference?
Severson et al.
Arch Ophthalmol 2003;121:386-390.
ABSTRACT
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Corneal blindness in a southern Indian population: need for health promotion strategies
Dandona and Dandona
Br. J. Ophthalmol. 2003;87:133-141.
ABSTRACT
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The Bhaktapur eye study: ocular trauma and antibiotic prophylaxis for the prevention of corneal ulceration in Nepal
Upadhyay et al.
Br. J. Ophthalmol. 2001;85:388-392.
ABSTRACT
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Epidemiology and aetiological diagnosis of corneal ulceration in Madurai, south India
Srinivasan et al.
Br. J. Ophthalmol. 1997;81:965-971.
ABSTRACT
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Corneal ulceration in the developing world---a silent epidemic
WHITCHER and SRINIVASAN
Br. J. Ophthalmol. 1997;81:622-623.
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