This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Latif M. Hamed, MD; David T. Tse, MD; Joel S. Glaser, MD; Sandra Frazier Byrne; Norman J. Schatz, MD

Arch Ophthalmol. 1992;110(5):636-639.

Abstract
• The mechanisms by which optic nerve-sheath fenestration is effective remain speculative. Possibilities include surgical production of a cerebrospinal fluid filtration outlet or scarring in the subarachnoid space around the nerve in the vicinity of the fenestration site, with shifting of the pressure gradient from the nerve head to the retrobulbar portion. Two patients who underwent successful optic nerve-sheath fenestration developed a cystlike structure contiguous to the fenestration site, apparently in direct communication with the optic nerve sheaths. This was shown on magnetic resonance imaging (one patient) and orbital echography (both patients). These previously unreported observations may support the hypothesis that fenestration works by creating a filtration apparatus that controls the intravaginal pressure in the subarachnoid space surrounding the orbital segment of the optic nerve.

Author Affiliations
From the Bascom Palmer Eye Institute, University of Miami (Fla) School of Medicine. Dr Hamed is now with the Department of Ophthalmology, University of Florida College of Medicine, Gainesville.

Footnotes
Accepted for publication November 13, 1991.

Reprint requests to Department of Ophthalmology, University of Florida College of Medicine, PO Box 100284, Gainesville, FL 32610-0284 (Dr Hamed).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Macroglial Alterations after Isolated Optic Nerve Sheath Fenestration in Rabbit
Villain et al.
IOVS 2002;43:120-128.
ABSTRACT | FULL TEXT  

Effect of mitomycin C on the optic nerve in rabbits
Mietz et al.
Br J Ophthalmol 1997;81:584-589.
ABSTRACT | FULL TEXT  

Optic Nerve Sheath Decompression With Adjunctive Mitomycin and Molteno Device Implantation
Spoor et al.
Arch Ophthalmol 1994;112:25-26.
ABSTRACT  

Neuroimaging of the Optic Nerve After Fenestration for Management of Pseudotumor Cerebri
Skalka
Arch Ophthalmol 1993;111:161-161.
ABSTRACT