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Timothy D. Matthews, FCOphth; David G. Frazer, FCOphth; Darwin C. Minassian, FCOphth; Cherry F. Radford, MBCO; John K. G. Dart, DM

Arch Ophthalmol. 1992;110(11):1559-1562.

Abstract
• Disposable soft contact lenses have been marketed as a safer alternative to conventional soft lenses. We undertook a casecontrol study of patients attending the casualty unit of an eye hospital to quantify the relative risk of keratitis in disposable lens wear and to establish associated patterns of use. All eligible contact lens users were identified and asked to complete a questionnaire (n=242). Keratitis, microbial or sterile, was the most common complication in disposable lens users, occurring in 16 of 41 subjects. The relative risks for all lens types were estimated by comparison with rigid lenses (the referent). Both extended- and daily-wear disposable lenses were associated with higher risks of keratitis than other lens types including conventional extended-wear lenses. Poor hygiene, disinfectant system failure, and lens type may all account for these statistically significant trends.

Author Affiliations
From Moorfields Eye Hospital, London, England (Drs Matthews, Frazer, and Dart and Ms Radford) and the Department of Preventive Ophthalmology, Institute of Ophthalmology, London (Dr Minassian). The authors have no pecuniary or proprietary interest in any of the contact lenses, lens materials, or contact lens care products mentioned in this article.

Footnotes
Accepted for publication August 27, 1992.

Reprint requests to Academic Unit of Neuroscience, Charing Cross Hospital, Fulham Palace Rd, London, England W6 8RF (Dr Matthews).

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