This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Robert D. Yee, MD; Martin R. Farlow, MD; David A. Suzuki, PhD; Kathleen F. Betelak; Bernardino Ghetti, MD

Arch Ophthalmol. 1992;110(1):68-74.

Abstract
• Gerstmann - Sträussler - Scheinker disease is a familial disorder of progressive ataxia and dementia in adulthood with extrapyramidal signs in some families. Neuro-ophthalmic examinations and eye movement recordings were performed in members of a large Indiana kindred. Five affected members and 11 members at risk were studied. Eye movements were recorded with videotape, electro-oculography, and/or magnetic scleral search coil. All affected members had abnormal eye movements characteristic of extrapyramidal diseases and cerebellar disorders. Nine members at risk had normal eye movements, but two others had slightly abnormal eye movements. Neuro-ophthalmic examination and eye movement recordings might be helpful in detecting early signs of Gerstmann-Sträussler-Scheinker disease in persons at risk.

Author Affiliations
From the Departments of Ophthalmology (Drs Yee and Suzuki and Ms Betelak), Neurology (Dr Farlow), and Pathology (Dr Ghetti), Indiana University School of Medicine, Indianapolis.

Footnotes
Accepted for publication August 10, 1991.

Reprint requests to the Department of Ophthalmology, 702 Rotary Cir, Indiana University Medical Center, Indianapolis, IN 46202-5124 (Dr Yee).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Novel prion protein gene mutation presenting with subacute PSP-like syndrome
Rowe et al.
Neurology 2007;68:868-870.
ABSTRACT | FULL TEXT