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Retinal Artery Obstruction and Atheromas Associated With Non-Hodgkin's Large Cell Lymphoma (Reticulum Cell Sarcoma)
J. Donald M. Gass, MD;
Henry L. Trattler, MD
Arch Ophthalmol. 1991;109(8):1134-1139.
Abstract
• A 71-year-old woman developed branch retinal artery obstruction as the presenting manifestation of a large cell non-Hodgkin's lymphoma. Multifocal chorioretinal scars were present in the same eye. She experienced progressive visual loss accompanied by development of multiple yellow retinal arterial wall plaques, extension of retinal opacification into other quadrants, and increasing vitreous cellular infiltration. Clinical diagnoses included branch retinal arterial obstruction caused by toxoplasmosis retinitis, multifocal choroiditis and panuveitis simulating the presumed ocular histoplasmosis syndrome, vitiliginous chorioretinitis, and the acute retinal necrosis syndrome. Four months after on-set, the right eye was blind and was enucleated. Histopathologic examination revealed extensive lymphomatous infiltration and necrosis of the retina and optic nerve. The retinal arteries were partly obstructed by lymphomatous infiltration and atheromas. Subsequently, the left eye and central nervous system were involved by lymphoma.
Author Affiliations
From the Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami (Fla) School of Medicine.
Footnotes
Accepted for publication April 10, 1991.
Presented at the Verhoeff Ophthalmological Society Meeting, Boston, Mass, April 14, 1989.
Reprint requests to Bascom Palmer Eye Institute, PO Box 016880, Miami, FL 33101 (Dr Gass).
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