This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

J. Sebag, MD

Arch Ophthalmol. 1991;109(7):966-971.

Abstract
• Age-related differences in vitreoretinal adhesion were investigated in 59 human eyes from donors aged from 33 weeks of gestation to 94 years with the use of dark-field and electron microscopy of whole vitreous. In all eyes from individuals aged 21 years or older, dissection of the retina off the vitreous resulted in cleavage between the vitreous cortex and the internal limiting lamina. However, in six (40%) of 15 eyes from individuals aged 20 years or younger, the internal limiting lamina remained adherent to the vitreous cortex in an area that encompassed the macula, temporal arcades, and peripapillary posterior pole. Ultrastructural studies revealed inner portions of Müller's cells that were attached to the posterior aspect of the internal limiting lamina. These results suggested that, in youth, there is adhesion between the vitreous cortex and internal limiting lamina that is stronger than Müller's cell itself and is topographically more extensive than previously thought.

Author Affiliations
From the Doheny Eye Institute, University of Southern California, Los Angeles, and the Eye Research Institute of Retina Foundation, Harvard Medical School, Boston, Mass. Dr Sebag is now in private practice in Huntington Beach, Calif.

Footnotes
Accepted for publication February 27, 1991.

Reprint requests to Pacifica Tower, 18800 Delaware St, Eleventh Floor Suite, Huntington Beach, CA 92648 (Dr Sebag).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Vitreous: the resplendent enigma
Sebag
Br J Ophthalmol 2009;93:989-991.
FULL TEXT  

Retinal Hemorrhages in Children Following Fatal Motor Vehicle Crashes: A Case Series
Kivlin et al.
Arch Ophthalmol 2008;126:800-804.
ABSTRACT | FULL TEXT  

Safety of In Vivo Pharmacologic Vitreolysis with Recombinant Microplasmin in Rabbit Eyes
Sakuma et al.
IOVS 2005;46:3295-3299.
ABSTRACT | FULL TEXT  

Late Retinal Detachment in Patients Born Prematurely: Outcome of Primary Pars Plana Vitrectomy
Jandeck et al.
Arch Ophthalmol 2004;122:61-64.
ABSTRACT | FULL TEXT  

Does Soccer Ball Heading Cause Retinal Bleeding?
Reed et al.
Arch Pediatr Adolesc Med 2002;156:337-340.
ABSTRACT | FULL TEXT  

Elevated Levels of Proteolytic Enzymes in the Aging Human Vitreous
Vaughan–Thomas et al.
IOVS 2000;41:3299-3304.
ABSTRACT | FULL TEXT  

Papillofoveal Traction in Macular Hole Formation: The Role of Optical Coherence Tomography
Chauhan et al.
Arch Ophthalmol 2000;118:32-38.
ABSTRACT | FULL TEXT  

Variations of posterior vitreous detachment
Kakehashi et al.
Br J Ophthalmol 1997;81:527-532.
ABSTRACT | FULL TEXT  

Biochemical Abnormalities in Vitreous of Humans With Proliferative Diabetic Retinopathy
Sebag et al.
Arch Ophthalmol 1992;110:1472-1476.
ABSTRACT