Neuro-ophthalmic complications of interleukin 2 therapy
D. I. Friedman, E. H. Hu and A. A. Sadun
Doheny Eye Institute, University of Southern California, Los Angeles 90033.
We describe three patients who experienced several types of visual problems
while receiving interleukin 2 therapy for melanoma or lymphoma. Their
symptoms included diplopia, binocular negative scotomata, scintillating
scotomata, and palinopsia. All symptoms eventually resolved following
discontinuation of therapy. It appears that focal neurologic deficits that
affect the visual system may complicate interleukin 2 administration.
