Acanthamoeba keratitis in non-contact lens wearers
S. Sharma, M. Srinivasan and C. George
Department of Ocular Microbiology, Aravind Eye Hospital, Madurai, India.
Nine cases of Acanthamoeba keratitis not associated with contact lens wear
were diagnosed between July 1987 and August 1989. Patients were treated
with topical neomycin-polymyxin B-bacitracin (Neosporin) drops alone or in
combination with either miconazole nitrate or ketoconazole drops. At the
time of data collection four patients were available for follow-up for an
average of 4 months; however, four patients were unavailable for follow-up
and one is still undergoing treatment. In four patients corneal infiltrates
cleared completely with topical medication (Neosporin, two patients;
Neosporin plus miconazole, two patients). Simple laboratory methods were
found to be adequate for the diagnosis of Acanthamoeba keratitis. Therapy
with Neosporin drops can result in resolution of corneal infiltrates due to
Acanthamoeba species.
Identification and Distribution of Acanthamoeba Species Genotypes Associated with Nonkeratitis Infections
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Use of 18S rRNA Gene-Based PCR Assay for Diagnosis of Acanthamoeba Keratitis in Non-Contact Lens Wearers in India
Pasricha et al.
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Patient characteristics, diagnosis, and treatment of non-contact lens related Acanthamoeba keratitis
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Fluorescent Oligonucleotide Probes for Clinical and Environmental Detection of Acanthamoeba and the T4 18S rRNA Gene Sequence Type
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Acanthamoeba keratitis: multicentre survey in England 1992-6
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Br. J. Ophthalmol. 1998;82:1387-1392.
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Antimicrobial management of presumed microbial keratitis: guidelines for treatment of central and peripheral ulcers
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Br. J. Ophthalmol. 1998;82:137-145.
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Risk factors for acanthamoeba keratitis in contact lens users: a case-control study
Radford et al.
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Acanthamoeba keratitis
Seal
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