Trazodone-induced palinopsia
M. S. Hughes and S. Lessell
Department of Ophthalmology, Harvard Medical School, Boston, MA.
Palinopsia refers to the persistence or reappearance of an image of a
recently viewed object. Typically, patients with palinopsia have other
visual symptoms or signs, and the underlying cause is a structural lesion
of the posterior portions of the cerebral hemispheres. However, we treated
three patients who experienced palinopsia as an isolated symptom,
apparently as a side effect of trazodone hydrochloride therapy for
depression. The palinopsia was dose related and disappeared with reduction
or cessation of therapy.
