You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 108 No. 3, March 1990 TABLE OF CONTENTS
  Archives
  •  Online Features
  ARTICLE
 This Article
 • Reply to article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal

Electrophysiological changes in juvenile diabetics without retinopathy

S. Juen and G. F. Kieselbach
Department of Ophthalmology, University of Innsbruck, Austria.

Several components of the electroretinogram were studied in 31 juvenile diabetics and 15 age-matched normal controls. The diabetic group consisted of 18 patients without retinopathy and 13 with mild background retinopathy. Oscillatory potentials were measured at low-stimulation energies. Significantly reduced amplitudes and component-specific delayed peak implicit times were found in both diabetic groups compared with the data from the controls. Similar results were obtained in the photopic and scotopic electroretinogram. From these findings, we suggest that retinal dysfunction is already present in juvenile diabetics without photographic evidence of retinopathy after a mean duration of diabetes of 7 years.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Retinal ganglion cells in diabetes
Kern and Barber
J. Physiol. 2008;586:4401-4408.
ABSTRACT | FULL TEXT  

Lower Somatostatin Expression Is an Early Event in Diabetic Retinopathy and Is Associated With Retinal Neurodegeneration
Carrasco et al.
Diabetes Care 2007;30:2902-2908.
ABSTRACT | FULL TEXT  

Topical Administration of Nepafenac Inhibits Diabetes-Induced Retinal Microvascular Disease and Underlying Abnormalities of Retinal Metabolism and Physiology
Kern et al.
Diabetes 2007;56:373-379.
ABSTRACT | FULL TEXT  

An Electrophysiological Study of Retinal Function in the Diabetic Female Rat
Ramsey et al.
IOVS 2006;47:5116-5124.
ABSTRACT | FULL TEXT  

Early vascular and neuronal changes in a VEGF transgenic mouse model of retinal neovascularization.
van Eeden et al.
IOVS 2006;47:4638-4645.
ABSTRACT | FULL TEXT  

Reduced response of retinal vessel diameters to flicker stimulation in patients with diabetes
Garhofer et al.
Br. J. Ophthalmol. 2004;88:887-891.
ABSTRACT | FULL TEXT  

Towards optimal filtering of "standard" multifocal electroretinogram (mfERG) recordings: findings in normal and diabetic subjects
Han et al.
Br. J. Ophthalmol. 2004;88:543-550.
ABSTRACT | FULL TEXT  

Oscillatory Potential Analysis and ERGs of Normal and Diabetic Rats
Hancock and Kraft
IOVS 2004;45:1002-1008.
ABSTRACT | FULL TEXT  

Diabetes-Induced Dysfunction of the Glutamate Transporter in Retinal Muller Cells
Li and Puro
IOVS 2002;43:3109-3116.
ABSTRACT | FULL TEXT  

Assessment of early retinal changes in diabetes using a new multifocal ERG protocol
Shimada et al.
Br. J. Ophthalmol. 2001;85:414-419.
ABSTRACT | FULL TEXT  

Foveal Dysfunction and Central Visual Field Loss in Glaucoma
Weiner et al.
Arch Ophthalmol 1998;116:1169-1174.
ABSTRACT | FULL TEXT  

Seeing Beyond Retinopathy in Diabetes: Electrophysiological and Psychophysical Abnormalities and Alterations in Vision
Ewing et al.
Endocr. Rev. 1998;19:462-476.
ABSTRACT | FULL TEXT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1990 American Medical Association. All Rights Reserved.