Solitary orbital involvement with juvenile xanthogranuloma
C. L. Shields, J. A. Shields and H. W. Buchanon
Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107.
A newborn girl was noted to have a smooth superonasal orbital and preseptal
mass at the time of birth. The mass enlarged slightly over 3 months and a
biopsy revealed histiocytes and Touton giant cells, compatible with
juvenile xanthogranuloma. The infant had no other manifestations of
juvenile xanthogranuloma. The mass subsided after systemic corticosteroid
therapy was administered. Solitary orbital involvement with juvenile
xanthogranuloma is exceedingly rare and most of these patients are found to
lack the typical cutaneous lesions. Observation, oral prednisone, or
low-dose radiotherapy are recommended forms of treatment.
