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Incidence in Rochester, Minn, 1950 Through 1982

Thomas J. Liesegang, MD; L. Joseph Melton III, MD; Peter J. Daly, MD; Duane M. Ilstrup, MS

Arch Ophthalmol. 1989;107(8):1155-1159.

Abstract
• Over the period 1950 through 1982, 122 Rochester, Minn residents had their first episode of ocular herpes simplex virus infection, for an age- and sex-adjusted incidence of 8.4 new cases per 100000 person-years (95% confidence intervals [CI], 6.9 to 9.9 cases). These initial episodes involved lid or conjunctiva in 54%, superficial cornea in 63%, deeper cornea in 6%, and uveitis in 4%. An additional 29 residents had episodes of ocular herpes other than their first. Altogether, these 151 residents had 294 episodes of ocular herpes simplex infection, for an adjusted incidence of 20.7 episodes per 100000 person-years (95% CI, 18.3 to 23.1 episodes). Age-adjusted rates by sex were comparable. There were no seasonal trends in incidence, but rates increased with time. On January 1, 1980, the prevalence of a history of ocular herpes simplex infection was 149 per 100000 population (95% CI, 115 to 183).

Author Affiliations
From the Departments of Ophthalmology (Dr Liesegang) and Health Science Research (Drs Melton and Daly and Mr Ilstrup), Mayo Clinic and Foundation, Rochester, Minn.

Footnotes
Accepted for publication February 27, 1989.

Portions of this work were submitted as a candidate thesis for membership in the American Ophthalmological Society and accepted by the committee on theses.

Reprint requests to the Division of Ophthalmology, Mayo Clinic Jacksonville, 4500 San Pablo Rd, Jacksonville, FL 32224 (Dr Liesegang).

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