Granulomatous uveitis in Crohn's disease. A clinicopathologic case report

J. F. Salmon, J. P. Wright, R. M. Bowen and A. D. Murray
Department of Ophthalmology, Groote Schuur Hospital, South Africa.

Recurrent episodes of uveitis occurred in a young male patient with clinical as well as radiologic and histologic evidence of Crohn's ileocolitis. His left eye became blind and painful, and was enucleated. Histopathologic examination of the eye revealed a panuveitis with evidence of granuloma formation in the choroid. While granulomatous inflammation has previously been demonstrated in extraintestinal sites, to our knowledge, this is the first histopathologic evidence of granuloma formation within the eye in Crohn's disease.