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Pseudo-Schnabel's Cavernous Degeneration of the Optic Nerve Secondary to Intraocular Silicone Oil
Carol L. Shields, MD;
Ralph C. Eagle, Jr, MD
Arch Ophthalmol. 1989;107(5):714-717.
Abstract
• A 29-year-old man sustained severe trauma to his left eye requiring corneoscleral wound repair and retinal detachment repair. Because of a persistent retinal detachment, he underwent vitrectomy and silicone oil implantation into the vitreous cavity. Over the ensuing 2 years 4 months, the eye gradually became glaucomatous, blind, and painful, requiring enucleation. Histopathologic examination revealed that coalescent globules of silicone oil had infiltrated the entire length of the attached atrophic optic nerve. Superficially reminiscent of the changes seen in Schnabel's cavernous optic atrophy, this observation provides evidence for the theory of Zimmerman et al concerning the pathogenesis of cavernous degeneration of the optic nerve in glaucomatous eyes.
Author Affiliations
From the Department of Pathology, Wills Eye Hospital, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pa.
Footnotes
Accepted for publication December 20, 1988.
Reprint requests to Oncology Service (Dr Shields) or Pathology Department (Dr Eagle), Wills Eye Hospital, Ninth and Walnut streets, Philadelphia, PA 19107.
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