This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (89)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

David Stern, MS; Robert W. Schoenlein, MS; Carmen A. Puliafito, MD; Ernest T. Dobi, PhD; Reginald Birngruber, PhD; James G. Fujimoto, PhD

Arch Ophthalmol. 1989;107(4):587-592.

Abstract
• We produced corneal excisions with nanosecond (ns)-, picosecond-, and femtosecond (fs)-pulsed lasers at visible wavelengths. The threshold energy for ablation was proportional to the square root of the pulse duration and varied from 2.5 microjoules (µJ) at 100 fs to 500 µJ at 8 ns. Excisions made with picosecond and femtosecond lasers were ultrastructurally superior to those made with nanosecond lasers and, at pulse energies near threshold, showed almost as little tissue damage as excisions made with excimer lasers at 193 nm. We conclude that ultra-short-pulsed lasers at visible and near-infrared wavelengths are a possible alternative to excimer lasers for corneal surgery and might have advantages over conventional ophthalmic neodymium-YAG lasers for some intraocular applications.

Author Affiliations
From the Laser Research Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston (Mr Stern and Drs Puliafito and Dobi); and the Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge (Mr Schoenlein and Dr Fujimoto). Dr Birngruber is visiting from the H. Wacker Laboratory, Augenklinik der Universität München, Munich, Federal Republic of Germany.

Footnotes
Accepted for publication January 13, 1989.

Reprint requests to Laser Research Laboratory, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114 (Dr Puliafito).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Intratissue Refractive Index Shaping (IRIS) of the Cornea and Lens Using a Low-Pulse-Energy Femtosecond Laser Oscillator
Ding et al.
IOVS 2008;49:5332-5339.
ABSTRACT | FULL TEXT  

Femtosecond laser-assisted corneal flap cuts: morphology, accuracy, and histopathology.
Holzer et al.
IOVS 2006;47:2828-2831.
ABSTRACT | FULL TEXT  

Intrastromal lamellar femtosecond laser keratoplasty with superficial flap
Jonas
Br J Ophthalmol 2003;87:1195-1195.
FULL TEXT  

Precise Ablation of Skin With Reduced Collateral Damage Using the Femtosecond-Pulsed, Terawatt Titanium-Sapphire Laser
Frederickson et al.
Arch Dermatol 1993;129:989-993.
ABSTRACT