Does pigmentation affect the trabecular meshwork?
D. H. Johnson
Department of Ophthalmology, Mayo Clinic, Rochester, Minn. 55905.
Pigment has been associated with glaucoma in pigment dispersion syndrome
and in intraocular lens-associated pigment dispersion. Human eyes with
segmental pigmentation of the trabecular meshwork may provide a controlled
model to study the effects of pigment on the meshwork. Nine normal human
eye bank eyes with segmental pigmentation of the trabecular meshwork were
examined for pigment-associated differences in trabecular cellularity or
morphology. Cellularity was examined with four methods: cells per
histologic section, cells per length of tissue, cells per overall area, and
cells per solid tissue. The simplest method, cells per histologic section,
gave results equivalent to the other methods. No differences in cellularity
or morphology were found between pigmented and nonpigmented areas.
