A comparison of the clinical variations of the iridocorneal endothelial syndrome
M. C. Wilson and M. B. Shields
Department of Ophthalmology, Duke University Eye Center, Durham, NC 27710.
Iridocorneal endothelial syndrome is generally considered to have three
major variations: Chandler's syndrome, progressive (essential) iris
atrophy, and the Cogan-Reese syndrome. To better understand the clinical
significance of this classification, we studied the medical records of 37
consecutive patients from our practice, comparing the presentation and
course of the three subgroups. Chandler's syndrome was the most common
clinical variant within this spectrum of disease (21 cases). Patients with
Chandler's syndrome had more severe corneal edema than the rest of the
group, while those with progressive iris atrophy (8 cases) or the
Cogan-Reese syndrome (8 cases) had worse secondary glaucoma.
